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Selected References and Presentations

To view a reference, please click on my name in the author list.  If Supplementary documents are available, the link to those documents are provided at the end of the reference.

Biotechnology - plasmid design, technology development

  1. Krause, C.D., Izotova, L.S., and Pestka, S.  Development of Multifunctional Plasmids for Diverse Biotechnological Applications, book chapter for “Plasmids: Genetics, Applications, and Health”, (2012, 1st ed., 2014, 2nd ed.), Nova Publishing

  2. Krause, C.D., and Pestka, S. (2013), Toward the Development of Real-Time Cellular Kinetic Assays to Characterize Inhibitors of Cytokine Signaling, OA Bioch. 1(2), 17.

  3. Krause, C.D., Izotova, L.S., and Pestka, S. (2013), Analytical Use of Multi-Protein Fluorescence Resonance Energy Transfer to Demonstrate Membrane-Facilitated Interactions Within Cytokine Receptor Complexes, Cytokine 64(1), 298-309. Supplementary documents

  4. Krause, C.D., Izotova, L.S., Ren, G., Yuan, Z.R., Shi, Y. Chen, C.-C., Ron, Y., and Pestka, S. (2012) Efficient Coexpression of Bicistronic Proteins in Mesenchymal Stem Cells by Development and Optimization of a Multi-Functional Plasmid, Stem Cell Research & Therapy 2(2), 15. Supplmentary documents

  5. Krause, C.D., Mei, E., Xie, J., Jia, Y., Bopp, M.A., Hochstrasser, R.M., and Pestka, S. (2002) Seeing the light: preassembly and ligand-induced changes of the interferon g receptor complex in cells. Mol.Cell Proteomics.  1(10), 810-815.

  6. Goldman, L.A., Cutrone, E.C., Kotenko, S.V., Krause, C.D., and Langer, J.A. (1996) Modifications of vectors pEF-BOS, pcDNA1 and pcDNA3 result in improved convenience and expression, Biotechniques 21, 1013-1015.

Interferon and interferon-like Interleukins - structure and signaling

  1. Krause, C.D., and Pestka, S. (2014), Is Stat1 Activated Catalytically Within Cells By the IFN-g Receptor Complex?, OA Biotechnology 3(1), 4.

  2. Krause, C.D., Digioia, G., Izotova, L.S., and Pestka, S. (2013), Improving Analysis of Fluorescence Resonance Energy Transfer in Live Cells: Application to Fluorescent Protein-Labeled Interferon Receptors, Cytokine 64(1), 272-85.  Supplementary documents

  3. Krause, C.D., Digioia, G., Izotova, L.S., Xie, J, Kim, Y.-S., Schwartz, B.J., Mirochnitchenko, O.V, and Pestka, S. (2013), Ligand-Independent Interaction of the Type I Interferon Receptor Complex is Necessary to Observe Its Biological Activity, Cytokine 64(1), 286-97.  Supplementary documents

  4. Krause, C.D., Mei, E., Mirochnitchenko, O.V., Lavnikova, N., Xie, J., Jia, Y., Hochstrasser, R., and Pestka, S. (2006) Interactions Among the Components of the Interleukin-10 Receptor Complex. Biochem. Biophys. Res. Commun. 340(2), 377-85.

  5. Krause, C.D., He, W., Kotenko, S.V., and Pestka, S. (2006) Modulation of the Activation of Stat1 by the IFN-g Receptor Complex. Cell Research 16, 113-123.

  6. Krause, C.D., Lavnikova, N., Xie, J., Mei, E., Mirochnitchenko, O.V., Jia, Y., Hochstrasser, R.M., and Pestka, S. (2006) Preassembly and Ligand-Induced Restructuring of the Chains of the IFN-g Receptor Complex: the Roles of Jak Kinases, Stat1 and the Receptor Chains. Cell Research 16, 55-69.

  7. Krause, C.D., and Pestka, S. (2006) Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives. Pharmacol Ther. 106(3), 299-346.

  8. Pestka S., Krause C.D., and Walter M.R. (2004)  Interferons, interferon-like cytokines, and their receptors. Immunol Rev. 202, 8-32.

  9. Pestka S, Krause C.D., Sarkar D., Walter M.R., Shi Y., Fisher P.B. (2004) Interleukin-10 and related cytokines and receptors. Annu Rev Immunol. 22, 929-79.

  10. Krause, C.D., Lunn, C.A., Izotova, L.S.,  Mirochnitchenko, O.,  Kotenko, S.V., Lundell, D.J., Narula, S.K., and Pestka, S. (2000) Studies on signaling of covalent heterodimers of interferon-g: evidence for one-sided signaling in the active tetrameric receptor complex, J. Biol. Chem. 275, 22995-23004.

  11. Livnah, O., Johnson, D.L., Stura, E.A., Farrell, F.X., Barbone, F.P., You, Y., Liu, K.D., Goldsmith, M.A., He, W., Krause, C.D., Pestka, S., Jolliffe, L.K., and Wilson, I.A. (1998) An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for function, Nat. Struct. Biol. 5, 993-1004.

  12. Kotenko, S.V., Krause, C.D., Izotova, L.S., Pollack, B.P., Wu, W., and Pestka, S. (1997) Identification and functional characterization of a second chain of the interleukin-10 receptor complex, EMBO J. 16, 5894-5903.

Presentations

  1. Audioslides to accompany reference 3 in biotechnology

  2. A portion of a pitch presentation describing the science behind a therapy

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