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Selected References and Presentations

To view a reference, please click on my name in the author list.  If Supplementary documents are available, the link to those documents are provided at the end of the reference.

Presentations

  1. Audioslides to accompany reference 3 in biotechnology

  2. A portion of a pitch presentation describing the science behind a therapy

Biotechnology - plasmid design, technology development

  1. Krause, C.D., Izotova, L.S., and Pestka, S.  Development of Multifunctional Plasmids for Diverse Biotechnological Applications, book chapter for “Plasmids: Genetics, Applications, and Health”, (2012, 1st ed., 2014, 2nd ed.), Nova Publishing

  2. Krause, C.D., and Pestka, S. (2013), Toward the Development of Real-Time Cellular Kinetic Assays to Characterize Inhibitors of Cytokine Signaling, OA Bioch. 1(2), 17.

  3. Krause, C.D., Izotova, L.S., and Pestka, S. (2013), Analytical Use of Multi-Protein Fluorescence Resonance Energy Transfer to Demonstrate Membrane-Facilitated Interactions Within Cytokine Receptor Complexes, Cytokine 64(1), 298-309. Supplementary documents

  4. Krause, C.D., Izotova, L.S., Ren, G., Yuan, Z.R., Shi, Y. Chen, C.-C., Ron, Y., and Pestka, S. (2012) Efficient Coexpression of Bicistronic Proteins in Mesenchymal Stem Cells by Development and Optimization of a Multi-Functional Plasmid, Stem Cell Research & Therapy 2(2), 15. Supplmentary documents

  5. Krause, C.D., Mei, E., Xie, J., Jia, Y., Bopp, M.A., Hochstrasser, R.M., and Pestka, S. (2002) Seeing the light: preassembly and ligand-induced changes of the interferon g receptor complex in cells. Mol.Cell Proteomics.  1(10), 810-815.

  6. Goldman, L.A., Cutrone, E.C., Kotenko, S.V., Krause, C.D., and Langer, J.A. (1996) Modifications of vectors pEF-BOS, pcDNA1 and pcDNA3 result in improved convenience and expression, Biotechniques 21, 1013-1015.

Interferon and interferon-like Interleukins - structure and signaling

  1. Krause, C.D., and Pestka, S. (2014), Is Stat1 Activated Catalytically Within Cells By the IFN-g Receptor Complex?, OA Biotechnology 3(1), 4.

  2. Krause, C.D., Digioia, G., Izotova, L.S., and Pestka, S. (2013), Improving Analysis of Fluorescence Resonance Energy Transfer in Live Cells: Application to Fluorescent Protein-Labeled Interferon Receptors, Cytokine 64(1), 272-85.  Supplementary documents

  3. Krause, C.D., Digioia, G., Izotova, L.S., Xie, J, Kim, Y.-S., Schwartz, B.J., Mirochnitchenko, O.V, and Pestka, S. (2013), Ligand-Independent Interaction of the Type I Interferon Receptor Complex is Necessary to Observe Its Biological Activity, Cytokine 64(1), 286-97.  Supplementary documents

  4. Krause, C.D., Mei, E., Mirochnitchenko, O.V., Lavnikova, N., Xie, J., Jia, Y., Hochstrasser, R., and Pestka, S. (2006) Interactions Among the Components of the Interleukin-10 Receptor Complex. Biochem. Biophys. Res. Commun. 340(2), 377-85.

  5. Krause, C.D., He, W., Kotenko, S.V., and Pestka, S. (2006) Modulation of the Activation of Stat1 by the IFN-g Receptor Complex. Cell Research 16, 113-123.

  6. Krause, C.D., Lavnikova, N., Xie, J., Mei, E., Mirochnitchenko, O.V., Jia, Y., Hochstrasser, R.M., and Pestka, S. (2006) Preassembly and Ligand-Induced Restructuring of the Chains of the IFN-g Receptor Complex: the Roles of Jak Kinases, Stat1 and the Receptor Chains. Cell Research 16, 55-69.

  7. Krause, C.D., and Pestka, S. (2006) Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives. Pharmacol Ther. 106(3), 299-346.

  8. Pestka S., Krause C.D., and Walter M.R. (2004)  Interferons, interferon-like cytokines, and their receptors. Immunol Rev. 202, 8-32.

  9. Pestka S, Krause C.D., Sarkar D., Walter M.R., Shi Y., Fisher P.B. (2004) Interleukin-10 and related cytokines and receptors. Annu Rev Immunol. 22, 929-79.

  10. Krause, C.D., Lunn, C.A., Izotova, L.S.,  Mirochnitchenko, O.,  Kotenko, S.V., Lundell, D.J., Narula, S.K., and Pestka, S. (2000) Studies on signaling of covalent heterodimers of interferon-g: evidence for one-sided signaling in the active tetrameric receptor complex, J. Biol. Chem. 275, 22995-23004.

  11. Livnah, O., Johnson, D.L., Stura, E.A., Farrell, F.X., Barbone, F.P., You, Y., Liu, K.D., Goldsmith, M.A., He, W., Krause, C.D., Pestka, S., Jolliffe, L.K., and Wilson, I.A. (1998) An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for function, Nat. Struct. Biol. 5, 993-1004.

  12. Kotenko, S.V., Krause, C.D., Izotova, L.S., Pollack, B.P., Wu, W., and Pestka, S. (1997) Identification and functional characterization of a second chain of the interleukin-10 receptor complex, EMBO J. 16, 5894-5903.

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